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MIGRINOL CAPSULES (Magnesium+Riboflavin+CoQ10)

Ang Migrinol ay isang nutraceutical supplement na iniinom upang pigilan ang paulit-ulit na migraine attacks. Ito ay nagtala ng level 2 recommendation ng American Headache Society, Canadian Headache Society at European Headache Society bilang supplement na nakatutulong sa pag-iwas sa migraine.

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    Magnesium

    Riboflavin

    Riboflavin

    Magnesium is an important mineral, playing a role in over 300 enzyme reactions in the human body. Its many functions include helping with muscle and nerve function, regulating blood pressure, and supporting the immune system. 

    Riboflavin

    Riboflavin

    Riboflavin

    Riboflavin is a B vitamin. It is involved in many processes in the body and is necessary for normal cell growth and function. It can be found in certain foods such as milk, meat, eggs, nuts, enriched flour, and green vegetables.

    CoQ10

    Riboflavin

    CoQ10

    Coenzyme Q10 is a vitamin-like substance found throughout the body, but especially in the heart, liver, kidney, and pancreas. It is eaten in small amounts in meats and seafood. Coenzyme Q10 can also be made in a laboratory.

    Reader's Corner

    Ano ang Migrinol??

    Ang Migrinol ay isang nutraceutical supplement na iniinom upang pigilan ang paulit-ulit na migraine attacks. Ito ay nagtala ng level 2 recommendation ng American Headache Society, Canadian Headache Society at European Headache Society bilang supplement na nakatutulong sa pag-iwas sa migraine.


    Nagtataglay ito ng mataas na sangkap ng magnesium na nagko-kontrol sa pagiging lubhang aktibo ng mga neurons na nagdudulot ng migraine. 


    Ito rin ay nakatutulong sa pagpigil ng synthesis at pag-release ng mga kemikal na nagdudulot ng sakit at pamamaga tuwing may migraine.


    Ang Riboflavin at CoQ10 ay nakatutulong upang magbigay ng enerhiya sa cells at nagpapanatili ng magandang mithocondrial funtion na nakatutulong

    sa pagkontrol ng pamamaga at sakit tuwing may migraine attack. 



    Bukod sa pagiging migraine preventive supplement ito rin ay:


    Magnesium 

    - Pinabubuti  ang metabolismo ng Insulin at glucose

    - Pinatitibay ang smooth muscles para sa mas maayos na daloy ng dugo

    - Pinagaganda ang lipid profile


    Riboflavin

    - Proteksyon laban sa Cardiac tissue Damage


    Coenzyme Q10

    - Pinabubuti ang cellular energy transformation

    - Pinipigilan ang pagkakaroon ng LDL (Bad Cholesterol)

    - Proteksyon laban sa paglapot ng dugo



    PAANO GAMITIN ANG MIGRINOL?


    Ang rekomendadong pag-inom ay isa hanggang dalawang kapsula kada araw. 

    Ang pinaka magandang oras ng pag-inom ay sa umaga, pagkatapos kumain

     o ayon sa payo ng iyong doktor.



    ADDITIONAL INFORMATION


    Studies revealed decreased levels of the micronutrients riboflavin, magnesium and coenzyme in plasma and in the brain of migraine. Mitochondrial dysfunction is Q10 play an important role in the production of energy in the mitochondria. Migraine treatment with a nutritional supplement might be of benefit for patients with recurrent migraine who cannot tolerate chemical drugs due to side effects or contra-indications due to concomitant diseases.  


     Magnesium

    Mg is the physiological antagonist at the NMDA-channel which is involved in the regulation of neuronal excitability.· Magnesium is needed in various physiological processes which influence the  pathophysiology of migraine (vasoconstriction, platelet inhibition, secretion of serotonin)· Some research has shown low brain. Magnesium levels during a migraines attack. Because it is thought that Magnesium deficiency and migraines may be related. Making it can important element for migraine aura and a natural remedy for migraines. Riboflavin (vitamin B2)· Riboflavin is a pre-cursor for Flavin-mononucleotide (FMN) and Flavin-adenine-dinucleotide(FAD). Both are responsible for electron-transport in the mitochondrial membrane. 


     Co-enzymes Q10

    Coenzymes Q10 is a vitamin-like compound which can be synthesized by the body from phenylalanine and tyrosine. Coenzymes Q10 is needed for all cellular processes requiring energy. Co-enzyme Q10 is an electron-carrier, transferring electrons from complex 1/complex 11 to cytochrome C. based on these observations, it seems plausible that a substitution of these micronutrients in migraine patients might be able to prevent or reduce the intensity of migraine attacks.  

    Reduction of maximal pain per migraine day.

    TABLE 1

      

    Reduction of maximal pain per migraine day.

    Reduction of migraine days

    Table 2: Reduction of migraine days

      

    1. Significant reduction in the headache impact test scoring compared to placebo.

    2. Decreased in the frequency of maximal pain in a day compared to placebo.

    3. Reduced migraine days compared to placebo.

    NUTRACEUTICALS IN THE TREATMENT OF HEADACHE 

    MAGNESIUM FOR MIGRAINE PREVENTION

    MAGNESIUM, FEVERFEW, AND RIBOFLAVIN:

    THERAPEUTIC USE IN MIGRAINE PREVENTION

    IMPROVEMENT OF MIGRAINE SYMPTOMS WITH A PROPRIETARY SUPPLEMENT CONTAINING RIBOFLAVIN, MAGNESIUM AND Q10: A RANDOIZED PLACEBP-CONTROLLED, DOUBLE-BLIND, MULTICENTER TRIAL

    Gaul2015_Article_ImprovementOfMigraineSymptomsW (pdf)Download
    JANAreprintandStudies_MAGNESIUM, FEVERFWE AND RIBOFLAVIN (pdf)Download
    Magnesium FOR MIGRAINE PREVENTION (pdf)Download
    Neutraceuticals in Migraine (pdf)Download
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